You play as two kinky space witches, sick and tired of an ignorant reality. You've chosen to conjure a new universe for yourselves and other kinky space witches. Only when you channel your powers together can you succeed. 2sWitches recreates the push & pull of switch/switch sex dynamics, in a two-player game environment. One player pulls symbols towards themselves, the other expels from themselves. Upon reaching accomplishment the players roles switch, and the distractions are removed from screen. Arielle Grimes describes the game as "a celebration of unity, as a trans woman and as a dyke."